Important Information & References

LINX®

1. tps://www.linxforlife.com/about-linx
2. Based on prospective observational study of 67 patients that underwent placement of LINX device between April 2012 and Dec. 2013, a 6-year single-center prospective case series of 100 patients that underwent MSA, and an IDE trial involving 100 patients implanted with LINX. Median operative times were 60 minutes, 47 minutes, and 39 minutes, respectively.
3. Based on pivotal IDE trial of 100 subjects at 14 clinical sites. Half the subjects (50/100) were discharged the same day as the surgery, and the other half were discharged the next day.
4. https://www.ncbi.nlm.nih.gov/pubmed/30031018
5. Based on 5-year prospective, multi-center, single-arm study observing 100 patients who were implanted with LINX, bothersome heartburn was 89% at baseline and decreased to 11.9% at 5 years. (p<0.001)
6. Ganz R. Edmundowicz S, Taiganides P, et al. Long-term Outcomes of Patients Receiving a Magnetic Sphincter Augmentation Device for Gastroesophageal Reflux. Clin Gastroenterol Hepatol. 2016. 14(5):671-7. Based on a study observing 100 patients who were implanted with LINX, daily use of PPIs decreased to 15.3% at 5 years. (p<0.001)
7. Ganz R. Edmundowicz S, Taiganides P, et al. Long-term Outcomes of Patients Receiving a Magnetic Sphincter Augmentation Device for Gastroesophageal Reflux. Clin Gastroenterol Hepatol. 2016. 14(5):671-7. Based on 5-year prospective, multi-center, single-arm study observing 100 patients implanted with LINX, regurgitation was 57% at baseline and decreased to 1.2% at 5 years. (p<0.001)